|
KMID : 0367420050480111193
|
|
Journal of Korean Pediatric Society
2005 Volume.48 No. 11 p.1193 ~ p.1200
|
|
|
Clinical Entities and Etiology of Invasive Bacterial Infections in Apparently Healthy Children
|
|
Lee Jun-Ho
Song Eun-Kyung
Lee Jin-A
Kim Nam-Hee
Kim Dong-Ho
Park Ki-Won
Choi Eun-Hwa
Lee Hoan-Jong
|
|
|
Abstract
|
|
|
Purpose: Invasive bacterial infection is a major cause of morbidity and mortality in children. Previously, we reported etiology of invasive infections in healthy children in 1985-1995. This study was performed to update etiology of invasive bacterial infections in the previously healthy children.
Methods: We reviewed medical records of 98 episodes of invasive bacterial infections in immunocompetent children at the Seoul National University Children’s Hospital in 1996-2004.
Results: The frequent pathogens identified over all age groups were Streptococcus pneumoniae (33 %) and Staphylococcus aureus(33%). The proportion of Salmonella species and Haemophilus influenzae has been declined to 4% each from 23% and 14%, respectively, compared to previous study. S. agalactiae was the most common isolate in the infants < or =3 months. Among the infants and children aged 3 months to 2 years and children of 2-5 years, S. pneumoniae(57%, 52%, respectively, in each group) was the most common isolates followed by S. aureus(17% and 24%, respectively). S. aureus was the most common isolates(73%) in children >5 years. Primary bacteremia was the most common clinical diagnosis(27%). S. pneumoniae was responsible for 42% of primary bacteremia, 50% of meningitis, and 69% of bacteremic pneumonia and empyema. S. aureus accounted for 80% of bone and joint infections. The case fatality rate was 8.1% for all invasive infections.
Conclusion: We reviewed frequency of bacterial agents of invasive infections in children. The data may be useful for pediatricians to select adequate empirical antibiotics in the management of invasive bacterial infections.
|
|
|
KEYWORD
|
|
|
Bacterial infections, Bacteremia, Meningitis, Streptococcus pneumoniae, Staphylococcus
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
 
|
|